Using condoms consistently for anal sex is the best solution. From what I know, you need to monitor your blood and kidney functions while on PrEP. If you bareback while on it, you can catch other STDs. I have been sexually active for the past two decades, and have never contracted STDs because I stick to the condom use. Nowadays, HIV infection is no longer a death sentence. But still why do we want to deal with a chronical disease which can be prevented?