Vaccination against COVID

[goji]

I have some sympathy with Moses's view that there should be some urgency to vaccine development.

However, I'd still want to see trial results for ~10,000 people in a double blind trial.

Here's an example of independent press comment on the Russian vaccine: https://www.nytimes.com/2020/08/11/w...-approval.html

Of course, I'd still like to see the west accelerate things a little. If we look at the Russian case, where Moses informs us that they've run some trials in hospital, it follows that they have probably deliberately infected people in order to check the results. I think that's a good idea, as long as they were volunteers.

In contrast, the Oxford vaccine has expanded the trial to Brazil & South Africa, in order to get more exposure to random infections.
Considering the potential to accelerate vaccine development, at minimal risk AND with a lower net death rate, I think deliberately infecting volunteers should be considered in the west as well. ie Copy some methods which must have been used in Russia.

Finally, if Mr Putin has announced this vaccine before a phase 3 trial is complete, then obviously if phase 3 trials show some side effects, then "commitment bias" will make it more difficult to cancel the vaccine.

[goji]

Another example of media comment.
I don't agree with everything in it, as the writer does not know what test Russia HAS done to prove the vaccine is effective. However, it does flag up the main concerns over the difference in approach & indentifies why Russia is so quick.

https://www.theguardian.com/commenti...e-or-effective

[Moses]

However, I'd still want to see trial results for ~10,000 people in a double blind trial.

Why you need trial results when Sputnik-V will be used in Russia? Govt told what they will not distribute vaccine abroad until time when local needs will be fulfilled. But they accepted offers form some countries to build up manufacturing plants in these countries on 50/50.

[goji]

Why you need trial results when Sputnik-V will be used in Russia?

I don't. My comments were based on what I would want to see before taking it myself.
If anyone else on the planet wants to take it based on their own assessment, that's their choice.

I'd happily take the Russian vaccine myself, as long as I could see independent test data, with a suitable sample size.
However, at present, it would appear that the main difference between the Russian vaccine and (for example), the Oxford vaccine, is the Russian one is declared available before any phase 3 trial results are published.

[latintopxxx]

I find it sad that some of us refuse to accept that anything good can come out of Russia....

[arsenal]

Caviar.

[francois]

Vodka.

[dinagam]

Vodka.

How beneficial is it if administered by injection or IV drip?

[francois]

How beneficial is it if administered by injection or IV drip?

I prefer by oral injection although I have read it can be by rectal injection.

[goji]

I find it sad that some of us refuse to accept that anything good can come out of Russia....

Has anyone here taken such a stance ?

Whether the vaccine is manufactured in Russia or the UK, knowing that in both cases there's pressure to bring a vaccine out as fast as possible, I'd want to see the same standard of trial results.

I've also had dealings with numerous Russians at my former employer. They were well educated and generally very impressive.