Re: Vaccination against COVID
Quote:
Originally Posted by
Moses
3. For vector vaccines all side effects are the same what has vector itself. If you choose safe vector then vaccine itself will be the same safe as vector is. If Oxford vaccine still need to be tested for safety reason then that means what choosen vector isn't safe enough or is not studied enough at past, "which is key difference"
yet the day before you said
Quote:
Originally Posted by
Moses
It is the same vector vaccine like Oxford. If chosen vector is safe, then vaccine itself is safe as well. In Sputnik-5 they use as a vector harmless for human adenovirus.
From the Oxford team:
Quote:
The ChAdOx1 vaccine is a chimpanzee adenovirus vaccine vector. This is a harmless, weakened adenovirus that usually causes the common cold in chimpanzees. ChAdOx1 was chosen as the most suitable vaccine technology for a SARS-CoV-2 vaccine as it has been shown to generate a strong immune response from one dose in other vaccines. It has been genetically changed so that it is impossible for it to grow in humans. This also makes it safer to give to children, the elderly and anyone with a pre-existing condition such as diabetes. Chimpanzee adenoviral vectors are a very well-studied vaccine type, having been used safely in thousands of subjects.
so if the Oxford teams' adenovirus vector "isn't safe enough or is not studied enough at past" what is the clinical evidence for the "key difference" between the Oxford and Sputnik-5 vector that you base your claim that the Sputnik-5 team "use as a vector harmless for human adenovirus" and thus phase III trial results are not required?
and the choice of the name "Sputnik" is historically neutral?
Re: Vaccination against COVID
Quote:
Originally Posted by
bkkguy
yet the day before you said
Quote:
It is the same vector vaccine like Oxford
You know - my English isn't best. Under "the same" I meant - it is also vector vaccine. I had no idea which vector they use (till now). Gamalei lab uses human adenovirus. It is studied enough. So for Sputnik-5 3rd phase of trial should just show how effective it is and how long antibodies will exists after been generated by vaccination. We will see it at next few months when medics and teachers will be vaccinated (vaccination is free and is by their choice, no forced vaccination).
And it is solely choice of Oxford how long and wide they want to test vaccine with shimpanze's adenovirus vector on phase 3. I have no idea how deep this virus is studied for to count vaccine safe or not.
Quote:
Originally Posted by
bkkguy
and the choice of the name "Sputnik" is historically neutral?
Should it be neutral? :)
Re: Vaccination against COVID
...love the game the Russians are playing...goading others working on a vaccine to hurry the fuck up...havent got all year to waste on niceties...
Re: Vaccination against COVID
Reading all the posts in this thread I come to a conclusion: Not only politicians are good immunologists as Mr. Trump or Duterte have proved many times but also being a member of a gay forum turns people into vaccination experts. I am very impressed. I admit that it is not my case. And I prefer to adhere to what truly reputable scientists have to say.
Re: Vaccination against COVID
Well said siscu58. That would be a great name for a vaccine I think. Much better than Sputnik.
Re: Vaccination against COVID
Even Duterte says he will take it in May 2021 AFTER a phase 3 trial.
1 Attachment(s)
Re: Vaccination against COVID
Meanwhile one more Russian state organisation announced today what they finished phase 2 of tests of another vaccine.
"Vector" institute. Located in the middle of Siberia. Formerly military facility and manufacturer of about 50% of Soviet biological weapons. Past 25 years they are developers of vaccines against Ebola, SARS and so on. Vector is WHO's reference laboratory. They have P-4 class laboratory and are one of two in world laboratories to whom WHO allows to work with smallpox (second is CDC lab in Atlanta).
https://www.globalsecurity.org/wmd/w...sia/vector.htm
"Vector" announced what they finished phase 2 with 89 volunteers, found zero side effects. They will start phase 3 from September. Their vaccine is "classical" vaccine with killed viruses.
Attachment 10253
Re: Vaccination against COVID
Quote:
Originally Posted by
Moses
Meanwhile one more Russian state organisation announced today what they finished phase 2 of tests of another vaccine.
"Vector" institute. Located in the middle of Siberia. Formerly military facility and manufacturer of about 50% of Soviet biological weapons. Past 25 years they are developers of vaccines against Ebola, SARS and so on. Vector is WHO's reference laboratory. They have P-4 class laboratory and are one of two in world laboratories to whom WHO allows to work with smallpox (second is CDC lab in Atlanta).
https://www.globalsecurity.org/wmd/w...sia/vector.htm
"Vector" announced what they finished phase 2 with 89 volunteers, found zero side effects. They will start phase 3 from September. Their vaccine is "classical" vaccine with killed viruses.
Attachment 10253
Presumably the Magnitsky Act and similar will be effective against any attempt to profit from these Russian vaccines
Re: Vaccination against COVID
Perhaps Alexei Navalny is part of the COVID-19 vaccine tests?
Re: Vaccination against COVID
Quote:
Originally Posted by
siscu58
Reading all the posts in this thread I come to a conclusion: Not only politicians are good immunologists as Mr. Trump or Duterte have proved many times but also being a member of a gay forum turns people into vaccination experts. I am very impressed. I admit that it is not my case. And I prefer to adhere to what truly reputable scientists have to say.
Exactly. Think I'll wait for something to get out of phase III trials, and be peer reviewed by the worldwide community of researchers and doctors who actually know what they're talking about.