I see the Vietnamese have said they’re in the market for the Russian vaccine and a few news stories about Putin selling it to other Asian countries - https://www.reuters.com/article/us-h...-idUSKCN25A0M0
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I see the Vietnamese have said they’re in the market for the Russian vaccine and a few news stories about Putin selling it to other Asian countries - https://www.reuters.com/article/us-h...-idUSKCN25A0M0
First photos from manufacturing plant: ready to delivery vaccine. Boxes labeled in Russian "Not for sale, for use in hospitals and clinics, check instruction inside". Bulbs labeled "keep freezed below -18C in dark place"
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It is sensible for governments to keep their options open.
The Russian vaccine MIGHT work very well with minimal side effects. However, this is generally considered unproven until there's a large and independent phase 3 trial. Quite a lot of drugs and vaccines don't pass the phase 3 trial.
Responsible governments can negotiate supply of a few thousand for their own phase 3 trial, followed up by millions for the population, conditional on trial results. And nutters like Duterte will say he'll inject himself and take the vaccine right now.
You still not got? It is the same vector vaccine like Oxford. If chosen vector is safe, then vaccine itself is safe as well. In Sputnik-5 they use as a vector harmless for human adenovirus. The only "side effects" possible - personal tolerability (?) to its components: allergy and in rare cases anaphilactique shock. That why it should be used in hospitals and clinics only. Only questionable moment for rest tests: how effective it will be and for how long time.
Shiploads of experimental phase 3 vaccines on the way to the Siberian gulags as we speak. At least I hope so.
A Day in the Life of Ivan Denisovich by Alexander Solzhenitsyn. The best book I have ever read.
1 It's a similar vaccine to the Oxford vaccine. No country has approved the Oxford vaccine without phase 3 trials.
2 The majority of countries in the world are waiting for phase 3 trial results before deciding to approve it for application. Mr Putin has decided not to wait for phase 3 trials, which is the key difference.
3 Large scale phase 3 trials are usually required to prove the vaccine is safe, with no side effects. As the side effects might only be evident in a small proportion of people, a large trial is normally considered necessary.
Which part of that have I not understood ?
1. Yes, because it is commercial vaccine and it need to be tested in full for sale, "which is key difference"
2. Yes, because Sputnik-5 is free to distribute state vaccine, "which is key difference"
3. For vector vaccines all side effects are the same what has vector itself. If you choose safe vector then vaccine itself will be the same safe as vector is. If Oxford vaccine still need to be tested for safety reason then that means what choosen vector isn't safe enough or is not studied enough at past, "which is key difference"
Looks like all 3.
Well, I have obviously failed to understand that a vaccine requires less testing if it's free issued rather than sold. I even thought the safety risks are the same, whether the vaccine is free or paid for.
The Philippines seems to think a phase 3 trial is required for this vaccine: https://www.dw.com/en/philippines-pl...ber/a-54548273
Oh well at least they're err'ing on the side of caution there, unlike their President giving out advice saying that poor Flipinos
should wash their masks in Petrol if they have nothing else and then when his staff issued a statement saying " well OBVIOUSLY the President was joking there" he immediately issued a second statement saying "no I bloody wasn't !!"
https://www.bbc.co.uk/news/world-asia-53605108
Weirdly on talking to a Flipino about this at the weekend ( who is a Duterte supporter actually) his take on it was that Duretrei said it as he was pissed off with the "poor people" who have totally ignored all government advice and it's THEIR FAULT that covid is running riot in the Ph's ( god for yet another politician takes any responsibility eh, some things never change !)